Evaluation of the antifungal activity of the essential oil of Pogostemon cablin (lamiaceae) against Candida glabrata

Authors

  • Eduardo Pimenta Secretaria Municipal de Saúde de Paulo Afonso - BA
  • Renata da Cruz Secretaria Municipal de Saúde de Paulo Afonso - BA
  • Hermes Diniz-Neto UFPB
  • Daniele Silva UFPB
  • Heloísa de Oliveira UFRN
  • Danieli Buccini Universidade Católica Dom Bosco
  • Edeltrudes Lima UFPB
  • Abrahão de Oliveira Filho UFCG

DOI:

https://doi.org/10.14808/sci.plena.2019.064601

Keywords:

Candida non-albicans, phytotherapy, Pogostemon cablin

Abstract

Invasive candidiasis is a growing threat among critically ill patients and is a significant cause of morbidity and mortality. Epidemiologically, non-albicans species are becoming relevant because they are becoming the most frequent causative agents of candidiasis. The indiscriminate use of drugs to combat the various strains of candidiasis has brought an expressive increase in the number of resistant yeasts. In this way, products of plant origin can be used as an substitute for synthetic antifungals agents. Based on this information, this research aimed to evaluate the possible antifungal activity of Pogostemon cablin (Lamiaceae) essential oil against Candida glabrata strains by microdilution technique for the determination of Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC). After the experiment, the product was found to inhibit one of the C. glabrata strains with a MIC of 256 μg/ml. The same value was obtained for MFC. Therefore, it can be concluded that the essential oil of P. cablin tested has an antifungal effect against the yeasts of C. glabrata.

Author Biographies

Hermes Diniz-Neto, UFPB

http://lattes.cnpq.br/8954433566483884

Daniele Silva, UFPB

http://lattes.cnpq.br/9018941238797596

Danieli Buccini, Universidade Católica Dom Bosco

http://lattes.cnpq.br/2449359296737282

Edeltrudes Lima, UFPB

http://lattes.cnpq.br/9406572870167006

Abrahão de Oliveira Filho, UFCG

http://lattes.cnpq.br/7440461731944347

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Published

2019-07-12

How to Cite

Pimenta, E., da Cruz, R., Diniz-Neto, H., Silva, D., de Oliveira, H., Buccini, D., … de Oliveira Filho, A. (2019). Evaluation of the antifungal activity of the essential oil of Pogostemon cablin (lamiaceae) against Candida glabrata. Scientia Plena, 15(6). https://doi.org/10.14808/sci.plena.2019.064601

Issue

Vol. 15 No. 6 (2019): Junho/June 2019

Section

Articles

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